Description_x000D_ Immunogen_x000D_ Recombinant protein encoding full-length SUG1 purified from E. coli._x000D_ Application_x000D_ For WB: Use at a dilution of 1:1,000. Optimal dilutions/concentrations should be determined by the researcher._x000D_ Physical form_x000D_ Phosphate-buffered saline, pH 7.4, containing no preservatives_x000D_ Disclaimer_x000D_ Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals._x000D_ Biochem/physiol Actions_x000D_ Human PSMC5 (also known as SUG1, p45, Rpt6 and Cim3) is a component of the 19S regulatory subunit of the 26S proteosome complex. It is one of the AAA ATPas found in the 19S regulatory complex that is thought to participate in the unfolding of ubiquitinated proteins in an ATP-dependent manner. It has also been shown to directly interact with the nucleotide excision repair protein XPB._x000D_ Features and Benefits_x000D_ Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.