Description_x000D_ General description_x000D_ X-prolyl aminopeptidase 3 (XPNPEP3) gene encodes a metalloenzyme belonging to the M24B (MEROPS) subfamily. This gene is highly conserved among eukaryotes and is mapped to human chromosome 22q13.2. XPNPEP3 exists in two isoforms, XPNPEP3 and XPNPEP3c, localized to the mitochondrial matrix and cytosol, respectively._x000D_ Immunogen_x000D_ XPNPEP3 purified recombinant protein_x000D_ Physical form_x000D_ Solution in Dulbecco′s Modified Eagle′s Medium with 10% fetal calf serum and 15 mM sodium azide._x000D_ Biochem/physiol Actions_x000D_ X-prolyl aminopeptidase 3 (XPNPEP3) detaches the amino acid present in the penultimate positioned-proline residue at the N-terminal region of the peptide. Increased levels of XPNPEP3 is observed in cancer. Mutation in XPNPEP3 gene is associated with cystic kidney disease.