Description_x000D_ General description_x000D_ Zinc finger protein 36 (ZFP36) is an AU-rich element-binding protein, which is present in all eukaryotes. It is a member of the TIS11 gene family. ZFP36 is an anti-inflammatory molecule. The gene is located on human chromosome 19q13.2._x000D_ Immunogen_x000D_ ZFP36 purified recombinant protein_x000D_ Physical form_x000D_ Solution in Dulbecco′s Modified Eagle′s Medium with 10% fetal calf serum and 15 mM sodium azide._x000D_ Disclaimer_x000D_ Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals._x000D_ Biochem/physiol Actions_x000D_ Zinc finger protein 36 (ZFP36) stimulates mRNA decay. It inhibits inflammation response by destabilizing proinflammatory mRNAs including c2, interleukin (IL)-6, IL-8 and IL-10. ZFP36 plays a vital role in tumorigenesis. It stimulates the degradation of AU-rich elements (AREs)-containing transcripts. ZFP36 post-transcriptionally regulates cytokine production.