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MOUSE IGA, KAPPA (TEPC 15)
Кат. №: M1421-1MG
Производитель: Sigma-Aldrich
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MOUSE IGA, KAPPA (TEPC 15)
Кат. №: M1421-1MG
Производитель: Sigma-Aldrich
Кол-во:
Цена по запросу
Товар оформляется под заказ
Кол-во:
Цена по запросу
Товар оформляется под заказ
Description_x000D_
General description_x000D_
IgA antibody is secretory antibody and is present abundantly in mucous linings of gastrointestinal, respiratory and genitourinary tracts, tears and saliva. Thus secretory IgA contributes to the humoral defense mechanism against the pathogens on mucosal surfaces_x000D_
IgA, κ from murine myeloma is produced by TEPC 15 tumor line that is pristane-induced plasmacytoma originated and carried intraperitoneally in BALB/c mice. The antibody is specific for κ chain of mouse IgA. The purified immunoglobulin preparation is non-reactive with anti-mouse IgM, IgG1, IgG2a, IgG2b, and IgG3._x000D_
The TEPC 15 tumor line that produces mouse IgA,k is pristane-induced plasmacytoma originated and carried intraperitoneally in BALB/c mice. Immunoglobulin G (IgG) belongs to the immunoglobulin family and is a widely expressed serum antibody. An immunoglobulin has two heavy chains and two light chains connected by a disulfide bond. It mainly helps in immune defense. It is a glycoprotein. IgG is a major class of immunoglobulin. Mouse consists of five immunoglobulin classes- IgM, IgG, IgA, IgD and IgE. IgA molecules in the serum are mostly dimeric. IgA is found in saliva, tracheobronchial secretions, genitourinary secretions, milk and colostrum._x000D_
Specificity_x000D_
Antigen Specificity: phosphoryl choline_x000D_
Application_x000D_
Anti-Mouse IgA, κ antibody was used as secondary antibody in ELISA and immunoflourescence._x000D_
IgA, Kappa from murine myeloma has been used in:_x000D_
• immunofluorescence assay_x000D_
• enzyme-linked immunosorbent assay (ELISA)_x000D_
• invasion assays_x000D_
• western blotting_x000D_
Biochem/physiol Actions_x000D_
Immunoglobulin G (IgG) helps in opsonization, complement fixation and antibody dependent cell mediated cytotoxicity._x000D_
Physical form_x000D_
Solution in 0.02 M Tris buffered saline, pH 8.0, containing 0.02% sodium azide_x000D_
Disclaimer_x000D_
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Related Categories
Antibodies, Mouse Myeloma Proteins, Purified Immunoglobulins, Sera and Immunoglobulins, Supplementary ProductsMore... Quality Level
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