Description_x000D_ General description_x000D_ The Mouse IL-15 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of mouse IL-15 in serum, plasma, cell culture supernatants and urine._x000D_ Immunogen_x000D_ Recombinant Mouse IL-15_x000D_ Application_x000D_ For research use only. Not for use in diagnostic procedures._x000D_ Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)_x000D_ Biochem/physiol Actions_x000D_ Interleukin 15 (IL-15) is a proinflammatory cytokine, expressed in monocytes and macrophages. IL-15 promotes T cell proliferation and adhesion to endothelial cells along with cluster of differentiation (CD44). IL-15 is a chemoattractant of natural killer (NK) cells and promotes its growth. IL-15 is associated with inflammatory disease like rheumatoid arthritis. Hypercholesteremia upregulates the expression of IL-15. Overexpression of IL-15 is implicated in cardiovascular disease and atherosclerosis. Polymorphism in IL-15 might cause celiac disease, a chronic autoimmune disease condition. The concentration of IL-15 in follicular fluid is inversely proportional to the size of the follicles and thus, affects the maturity of the oocytes. Polymorphism in IL-15 is associated with hepatocellular carcinoma._x000D_ Other Notes_x000D_ A sample Certificate of Analysis is available for this product._x000D_ Please type the word sample in the text box provided for lot number.