Description_x000D_ General description_x000D_ The Mouse MCP-1 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of mouse MCP-1 in serum, plasma and cell culture supernatants._x000D_ Immunogen_x000D_ Recombinant Mouse MCP1_x000D_ Application_x000D_ For research use only. Not for use in diagnostic procedures._x000D_ Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)_x000D_ Biochem/physiol Actions_x000D_ Monocyte chemoattractant protein-1 (MCP-1) or chemokine (C-C motif) ligand 2 (CCL2) is expressed in the suprachiasmatic nuclei (SCN) in the hypothalamus of mice. It has a role in the survival and proliferation of microglia. MCP-1 has been shown to activate GTPases like cell division control protein 42 (CDC42) and Ras-related C3 botulinum toxin substrate 1 (Rac1)._x000D_ Other Notes_x000D_ A sample Certificate of Analysis is available for this product._x000D_ Please type the word sample in the text box provided for lot number.