Description_x000D_ Packaging_x000D_ 5, 25 mg in glass bottle_x000D_ Biochem/physiol Actions_x000D_ MS4 (mercaptosteroid 4), a thiobenzothiazole-containing derivative of hydrocortisone, is a glucocorticoid receptor (GR) agonist that exhibits potent anti-inflammatory properties with reduced impact on insulin secretion. MS4 strongly repress CCL2 and CCL20 synthesis and secretion. MS4 exhibits reduced toxicity towards cultured b-cells, and does not promote adipogenesis or gluconeogenic gene expression in primary hepatocytes. MS4 could potentially be used to improve islet transplantation protocols.