Description General description N-Ethyl-N-isopropylpropan-2-aminium 3-(4-cyano-2,3,5,6-tetrafluorophenyl)-4-oxo-1,5-dioxaspiro[5.5]-undec-2-en-2-olate is a fluoroarylated-meldrum’s acid adduct. It can be prepared by reacting cyclohexyl-Meldrum’s acid with 2,3,4,5,6-pentafluorobenzonitrile in the presence of N,N-diisopropylethylamine and acetonitrile. Application This compound undergoes cycloreversion to form the fluoro(hetero)aryl ketene, which undergoes efficient coupling with nucleophiles and allows rapid incorporation of highly fluorinated α-fluoro(hetero)aryl acetic acid derivatives. Packaging 1 g in glass bottle Other Notes Selective Perfluoro- and Polyfluoroarylation of Meldrum’s Acid