Description_x000D_ General description_x000D_ Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards._x000D_ Naproxen belongs to the class of arylacetic acids and is used as a non-steroidal anti-inflammatory drug (NSAID). It is useful for the management of pain, inflammation and stiffness. It is also used in the treatment of rheumatoid arthritis and other painful musculoskeletal disorders._x000D_ Application_x000D_ Naproxen may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by high performance liquid chromatography (HPLC) technique._x000D_ These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements._x000D_ Biochem/physiol Actions_x000D_ Non-selective cyclooxygenase (COX-1 and COX-2) inhibitor._x000D_ Analysis Note_x000D_ These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available._x000D_ Other Notes_x000D_ This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis._x000D_ Footnote_x000D_ To see an example of a Certificate of Analysis for this material enter LRAA8968 in the slot below. This is an example certificate only and may not be the lot that you receive.