Description_x000D_ General description_x000D_ Neuraminidase enzymes are glycoside hydrolase enzymes that catalyze hydrolysis of terminal sialic acid residues. The most well-known are the viral nearamidases, which promote influenza virus release._x000D_ Application_x000D_ Neuraminidase from Vibrio cholerae has been used in a study to assess its role in the binding and uptake of cholera toxin by susceptible cells. It has also been used in a study to investigate the preparation of a sodium substrate and its use in a fluorometric assay of neuraminidase._x000D_ Neurminidase is used as a cell-surface probe for glycoconjugate distribution and in substrate specificity studies._x000D_ Packaging_x000D_ 1 unit in poly bottle_x000D_ 2 units in poly bottle_x000D_ Biochem/physiol Actions_x000D_ Vibrio cholerae neuraminidase has been shown to promote cholera toxin infection by binding the toxin and aiding in its uptake by cells._x000D_ Quality_x000D_ Preservative free._x000D_ Unit Definition_x000D_ One unit will liberate 1.0 μmole of N-acetylneuraminic acid per min at pH 5.0 at 37 °C using NAN-lactose or bovine submaxillary mucin, unless otherwise specified. Prices based on units using NAN-lactose as substrate._x000D_ Physical form_x000D_ Aqueous solution, pH 5.5, containing 0.15 M NaCl and 4 mM CaCl2._x000D_ Preparation Note_x000D_ Chromatographically purified.