Description_x000D_ Amino Acid Sequence_x000D_ Lys-Ile-Pro-Tyr-Ile-Leu_x000D_ Biochem/physiol Actions_x000D_ Neuromedin N is a hexapeptide that is related to neurotensin. Its precursor, proneuromedin N, is expressed in the adrenals, brain, gut and also in several cancers. In myoelectric activity, it has been reported to act in a similar manner as neurotensin, at a lesser degree of potency. Neuromedin N has been shown to increase the chemotaxis capacity of mouse lymphocytes and to modulate function of the hypothalamo-pituitary-adrenocortical axis in rats. Neuromedin N has been proposed to exert its actions via increase in intracellular Ca2+ concentration, although this is uncertain.