Description_x000D_ Packaging_x000D_ 5, 25 mg in glass bottle_x000D_ Biochem/physiol Actions_x000D_ NI-42 is a biased potent small molecule inhibitor of the bromodomain of the BRPF (bromodomain and PHD finger-containing) proteins, which are scaffolding proteins that assemble histone acetyltransferase (HAT) complexes of the MYST transcriptional coactivator family. NI-42 has an IC50 value of of 7.9 nM and is suitable for cellular and in vivo studies._x000D_ Legal Information_x000D_ Sold for research purposes under agreement from Pfizer Inc._x000D_ Pfizer is a registered trademark of Pfizer, Inc.