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NU7026
Кат. №: N1537-5MG
CAS: 154447-35-5
Производитель: Sigma-Aldrich
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Товар оформляется под заказ
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NU7026
Main image
Кат. №: N1537-5MG
CAS: 154447-35-5
Производитель: Sigma-Aldrich
Кол-во:
Фасовка:
Цена по запросу
Товар оформляется под заказ
Main image
Печать
NU7026
Кат. №: N1537-5MG
CAS: 154447-35-5
Производитель: Sigma-Aldrich
Кол-во:
Фасовка:
Цена по запросу
Товар оформляется под заказ
Description_x000D_ Application_x000D_ NU7026 has been used:_x000D_ • as a DNA-dependent protein kinase (DNA-PK) inhibitor, to pre-treat colon cancer cell_x000D_ • in kinase inhibitor experiments for treating zygotes with visible pronuclei post 20 h-human chorionic gonadotropin (hCG)_x000D_ • to determine its influence on cytotoxicity of dibenzo[def,p]chrysene on HepG2 cells_x000D_ Potent, ATP-competitive. IC50 = 0.23 μM. Selectivity over other PI3K-related kinases (IC50 = 13 μM for PI3K and >100 μM for ATM and ATR)._x000D_ Packaging_x000D_ 5 mg in glass bottle_x000D_ Biochem/physiol Actions_x000D_ Cell permeable, small molecule benzochromenone inhibitor of DNA-PK (DNA dependent protein kinase).
Related Categories
Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, DNA-dependent protein kinase (DNA-PK), Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, Kinase/Phosphatase Biology, N, P to Q, Protein kinase, DNA dependent, Serine/Threonine Kinase Biology, Serine/Threonine Kinase InhibitorsMore... Quality Level
Дорогой клиент, на сайте внедрена нейросеть для сбора информации о товаре. Это может привести к незначительным расхождениям в характеристиках продукции.
Description_x000D_ Application_x000D_ NU7026 has been used:_x000D_ • as a DNA-dependent protein kinase (DNA-PK) inhibitor, to pre-treat colon cancer cell_x000D_ • in kinase inhibitor experiments for treating zygotes with visible pronuclei post 20 h-human chorionic gonadotropin (hCG)_x000D_ • to determine its influence on cytotoxicity of dibenzo[def,p]chrysene on HepG2 cells_x000D_ Potent, ATP-competitive. IC50 = 0.23 μM. Selectivity over other PI3K-related kinases (IC50 = 13 μM for PI3K and >100 μM for ATM and ATR)._x000D_ Packaging_x000D_ 5 mg in glass bottle_x000D_ Biochem/physiol Actions_x000D_ Cell permeable, small molecule benzochromenone inhibitor of DNA-PK (DNA dependent protein kinase).
Related Categories
Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, DNA-dependent protein kinase (DNA-PK), Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, Kinase/Phosphatase Biology, N, P to Q, Protein kinase, DNA dependent, Serine/Threonine Kinase Biology, Serine/Threonine Kinase InhibitorsMore... Quality Level
Дорогой клиент, на сайте внедрена нейросеть для сбора информации о товаре. Это может привести к незначительным расхождениям в характеристиках продукции.