Description_x000D_ Application_x000D_ O-Phospho-L-serine has been used:_x000D_ • for the expression, purification and phosphorylation of protein_x000D_ • to study its chemical shift_x000D_ • to spectroscopically determine its pKa values using Raman spectroscopy_x000D_ Packaging_x000D_ 10 mg in autosample vial_x000D_ Biochem/physiol Actions_x000D_ O-Phospho-L-serine (L-SOP) is a molecule which resembles phosphatidylserine head group and it mediates partial inhibition of microglial phagocytosis of apoptotic cells. In zebrafish, L-SOP inhibits Müller glia proliferation and blocks cone cell regeneration in the light-damaged retina. In vivo, L-SOP acts as a substrate for CysM, a cysteine synthase from Mycobacterium tuberculosis._x000D_ Group III metabotropic glutamate receptor agonist (mGluR4, mGluR7, and mGluR8)._x000D_ Features and Benefits_x000D_ This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more._x000D_ Legal Information_x000D_ LOPAC is a registered trademark of Sigma-Aldrich Co. LLC