Description_x000D_ General description_x000D_ Chemical structure: macrolide_x000D_ Application_x000D_ Oligomycin from Streptomyces diastatochromogenes is used:_x000D_ • in the inhibition of mitochondrial ATP production Leigh syndrome (LS) cells._x000D_ • in ATP-linked respiration and maximal capacity respiration assay in astrocytes._x000D_ • in measurement of oxygen consumption rate (OCR) and extracellular acidification rates in breast cancer cell lines._x000D_ Packaging_x000D_ 100, 250 mg in glass bottle_x000D_ 25 mg in poly bottle_x000D_ 5 mg in glass bottle_x000D_ Biochem/physiol Actions_x000D_ Oligomycin belongs to the macrolide group of antibiotics. It inhibits mitochondrial ATP-synthase enzyme. Oligomycin interacts with ATP synthase subunit-c in the Fo portion and impairs proton transport._x000D_ Other Notes_x000D_ A mixture of oligomycins A, B, and C.