Description General description Oxalyl chloride is a commonly used chlorinating reagent that can be prepared by the reaction of oxalic acid and phosphorus pentachloride. Application Oxalyl chloride may be used in the following processes: • Preparation of Mosher′s acid chloride by reacting with Mosher′s acid in the presence of DMF. • Activation of dimethyl sulfoxide for use in the oxidation of long-chain alcohols to carbonyls. • Activation of α-keto carboxylic acids and N-heterocyclic carboxylic acids for alkynylation to form ynediones and N-heterocyclic ynones, respectively. Reactant involved in: • Synthesis of N-heterocyclic ynones and ynediones, used to activate carboxylic acids • Chlorination and halogenation • Three-component [3+2] cycloadditions • Reactions with organostannanes • Synthesis of cyclopentenones • Carbonylations, used as a carbonyl synthon Suitable for the synthesis of acid chlorides used to produce liquid crystals. Packaging 10 kg in Nowpak™ 5, 25, 100 g in ampule Legal Information ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC