Description_x000D_ General description_x000D_ Poly(ADP-ribose) synthesized after DNA damage is only present transiently and is rapidly degraded by poly(ADP-ribose) glycohydrolase. PARG hydrolyzes poly(ADP-ribose) at glycosidic (1′′-2′) linkage of ribose-ribose bond to produce free ADP-ribose._x000D_ Physical form_x000D_ Solution in 50 mM TRIS-HCl, pH 7.5, containing 100 mM sodium chloride, 0.2% NP-40, 50 mM imidazole and 10% glycerol._x000D_ Other Notes_x000D_ Human PARG is fused to a His-tag.