Description_x000D_ General description_x000D_ Peptidyl arginine deiminase is the enzyme that converts arginine into citrulline._x000D_ Application_x000D_ Peptidyl arginine deiminase has been used in a study that assessed promising novel biomarkers for the early diagnosis of rheumatoid arthritis. It has also been used in a study to investigate the autopathogenic correlation of periodontitis and rheumatoid arthritis._x000D_ Packaging_x000D_ 25 units in poly bottle_x000D_ Biochem/physiol Actions_x000D_ Calcium is required for peptidylarginine deiminase activity in vitro._x000D_ Unit Definition_x000D_ One unit will produce 1 μmole of N-α-benzoylcitrulline ethyl ester from BAEE per hr at 55 °C at pH 7.2._x000D_ Physical form_x000D_ Solution in 20 mM Tris-HCl, pH 7.4, containing 10 mM 2-mercaptoethanol, 1 mM EDTA and 10% glycerol