Description General description The racemic mixture of a pyridocarbazolo-cyclopentadienyl Ruthenium complex that acts as a ATP-binding site-targeting, reversible, and highly potent inhibitor of PIM-1 (IC50 = 0.5 and 3 nM for the (S)- and (R)-enantiomer, respectively) with ∼10-fold selectivity over GSK-3α (IC50 = 15 and 20 nM for the (S)- and (R)-enantiomer, respectively). Packaging 1 mg in Plastic ampoule Biochem/physiol Actions Cell permeable: no Primary Target PIM1 Product does not compete with ATP. Reversible: no Target IC50: 0.5 and 3 nM for the (S)- and (R)-enantiomer, of PIM-1, respectively Packaging Packaged under inert gas Warning Toxicity: Standard Handling (A) Reconstitution Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. Other Notes Bergman, H. and Meggers, E., 2006. Org. Lett.8, 5465. Legal Information Sold for research purposes only, pursuant to an agreement with University of Pennsylvania.