Description_x000D_ General description_x000D_ Chemical structure: quinolone_x000D_ Application_x000D_ Pipemidic acid is used to study DNA damage and mutagenic activity. It has been used to induce articular lesions in the neonatal mouse and is used to study human lymphocyte blastogenesis and γ-interferon production ._x000D_ Biochem/physiol Actions_x000D_ Pipemidic acid modulates (inhibits) bacterial DNA gyrase-dependent processes such as DNA polymerization, (ATP-dependent) DNA supercoiling, and chromosome fragmentation. Pipemidic acid has been shown to induce inhibition of lymphocyte DNA synthesis._x000D_ Analysis Note_x000D_ Very slightly soluble in water. It dissolves in diluted solutions of acids and of alkali hydroxides._x000D_ Other Notes_x000D_ 10g,100g_x000D_ Keep container tightly closed in a dry and well-ventilated place.Keep in a dry place_x000D_ Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. P7903.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.