Description_x000D_ General description_x000D_ Plasmin (EC 3.4.21.7) is a serine protease occurring in plasma as plasminogen. Upon activation via cleavage by plasminogen activators; plasmin solubilizes fibrin clots and activates and/or degrades compounds of the coagulation and complement systems. Plasminogen-Plasmin system has also been implicated in a wide variety of physiologic and pathologic processes, including tumor growth, invasion and metastasis._x000D_ Suitability_x000D_ Suitable to determine the activity of pure plasmin and to detect the activity of plasmin in plasma._x000D_ Principle_x000D_ The Plasmin Activity Assay Kit is based on the ability of plasmin to proteolytically cleave a synthetic substrate and release a fluorophore, AMC, which can be easily quantified by fluorescence microplate readers. This assay kit is simple, rapid, and can detect plasmin activity as low as 10 ng in a variety of samples.