Description_x000D_ Application_x000D_ Poly-L-lysine hydrochloride has been used to coat glass slides and coverslips to facilitate cell attachment._x000D_ Poly-lysine with mol. wt. >70,000 is useful in promoting cell adhesion to solid substrates._x000D_ Packaging_x000D_ 1 g in poly bottle_x000D_ 25, 100, 500 mg in poly bottle_x000D_ Biochem/physiol Actions_x000D_ L-Lysine is believed to prevent osteoporosis of bones, which is a characteristics of vascular calcification. Glutaric aciduria type I and pyridoxine-dependent epilepsy occurs due to lack of L-lysine catabolic pathway. Lysine participates in the regulation of NO (nitric oxide) synthesis. It possesses antiviral activity, therefore it is used in the treatment of Herpes simplex. L-Lysine is associated with a number of biochemical reactions such as acetylation, O-linked glycosylation, ubiquitination and protein methylation. Poly-L-lysine is considered as a biocompatible polymer and serves for the purpose of drug delivery across cell membrane. It is useful as one of the nanosized contrast agents in MRI (magnetic resonance imaging)._x000D_ Analysis Note_x000D_ Molecular weight based on viscosity._x000D_ Other Notes_x000D_ For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.