Description_x000D_ Application_x000D_ Polymyxin acylase, from Pseudomonas sp., is a N-myristoyl cleaving enzyme that has been used to determine the N-myristoyl peptide sequence and may be useful in cancer research since it has antitumor activity against murine and human tumor cells ._x000D_ Biochem/physiol Actions_x000D_ Polymyxin acylase, from Pseudomonas sp. deacylates polymyxin group antibiotics and long-chain fatty acyl groups of proteins. Polymyxin acylase has an affinity for long-chain fatty acyl proteins in human carcinoma cells ._x000D_ Quality_x000D_ Crude actone powder;_x000D_ Unit Definition_x000D_ One unit will hydrolyze 1 μmole of N-octanoyl-5-aminovaleric acid per min at pH 8.0 at 37°C.