Description_x000D_ General description_x000D_ Prazosin is a member of the class of α-adrenergic blockers. It is considered as a peripheral vasodilator antihypertensive agent. Prazosin is a derivative of quinazoline._x000D_ Application_x000D_ Prazosin hydrochloride has been used:_x000D_ • to block the α1adrenergic receptors that mediate sympathetic vasoconstriction in mice_x000D_ • as an α1-adrenoceptor blocker,administered intragastrically in rats_x000D_ • as a vasodilator,administered together with inuslin into the left ventricle of mice for the assessment of its effects on renal functions_x000D_ Biochem/physiol Actions_x000D_ Peripheral α1-adrenoceptor antagonist; vasodilator. Prazosin can be used to treat chronic posttraumatic stress disorder (PTSD). It plays a role in reducing blood pressure by relaxing blood vessels, hence used in the treatment of high blood pressure._x000D_ Features and Benefits_x000D_ This compound is a featured product for ADME Tox and Neuroscience research. Discover more featured ADME Tox and Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm._x000D_ This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more._x000D_ This compound is featured on the α1-Adrenoceptors, α2-Adrenoceptors and Melatonin Receptors pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here._x000D_ This compound was developed by Pfizer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here._x000D_ Packaging_x000D_ Bottomless glass bottle. Contents are inside inserted fused cone._x000D_ Caution_x000D_ Hygroscopic; light sensitive._x000D_ Legal Information_x000D_ LOPAC is a registered trademark of Sigma-Aldrich Co. LLC