Description_x000D_ General description_x000D_ Protamine sulfate (PS), a polycationic, positively charged protein is mostly made up of poly(l-arginine). It is obtained from salmon sperm protein._x000D_ Application_x000D_ Protamine sulfate salt from salmon has been used in the generation of protamine silica nanocomposites._x000D_ May be used for the removal of DNA from protein samples or for the purification of DNA binding proteins. It may be used as an alternative to polybrene in retroviral-mediated gene transfer._x000D_ Protamine in the form of solid lipid nanoparticles (SLN) promoted transfection with plasmid DNA more efficiently and with less cytotoxicity than comparable SLNs composed of Esterquat-1._x000D_ Protamine in the form of solid lipid nanoparticles (SLN) promoted transfection with plasmid DNA more efficiently and with less cytotoxicity than comparable SLNs composed of Esterquat-1._x000D_ Packaging_x000D_ 25, 100 g in poly bottle_x000D_ Biochem/physiol Actions_x000D_ Protamine sulfate is highly preferred in cardiovascular surgical procedures to reverse the anticoagulant properties of heparin. It is used for biomedical and biotechnological applications due to its biodegradablity._x000D_ Protamine sulfate is a small cationic protein that binds and precipitates DNA. Neutralizes the anticoagulant activity of heparin. Inhibits lipoprotein lipase._x000D_ Quality_x000D_ May contain insolubles as well as histones.