Description_x000D_ Amino Acid Sequence_x000D_ Myr-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-NH2_x000D_ General description_x000D_ Protein kinase A inhibitor fragment 14-22, myristoylated trifluoroacetate salt inhibits the protein kinase cAMP-activated catalytic subunit-α (PRKACA). The gene encoding it is localized on human chromosome 19p13.1._x000D_ Application_x000D_ Protein kinase A inhibitor fragment 14-22, myristoylated trifluoroacetate salt has been used in cell culture for pharmaceutical inhibition and activation studies._x000D_ Biochem/physiol Actions_x000D_ Mutations in the gene encoding protein kinase cAMP-activated catalytic subunit-α (PRKACA) have been associated with Cushing’s syndrome._x000D_ Cell permeable cAMP-dependent protein kinase (PKA) inhibitor