Description_x000D_ General description_x000D_ Pseudomonas exotoxin A is secreted by Pseudomonas aeruginosa. It is a member of the family mono-ADP-ribosyltransferases._x000D_ Packaging_x000D_ 0.5 mg in glass bottle_x000D_ Biochem/physiol Actions_x000D_ Pseudomonas exotoxin A functions as an anticancer agent._x000D_ It catalyses the transfer of ADP-ribose moiety of NAD+ to the histidine imidazole ring of diphthamide._x000D_ Shown to be toxic to animals and to cell lines, and to inhibit protein synthesis via ADP ribosylation of elongation factor 2._x000D_ Packaging_x000D_ Package size based on protein content._x000D_ Physical form_x000D_ Lyophilized powder containing Tris buffer, EDTA, NaCl and lactose