Description_x000D_ General description_x000D_ (R)-(-)-Phenylephrine hydrochloride is an adrenergic agent, which functions as a β-receptor sympathomimetic drug._x000D_ Application_x000D_ (R)-(-)-Phenylephrine hydrochloride has been used:_x000D_ • in the preparation and culturing of cardiocytes and fibroblasts_x000D_ • to stimulate myocardial strips to measure slice contraction_x000D_ • in primary cardiomyocyte culture to show the effect of Kruppel-like factors (KLF) on cardiac hypertrophy in vivo_x000D_ • to evaluate the pharmacological response of embryonic stem cell (ESC)-derived cardiomyocytes_x000D_ • to pharmacologically rescue GATA (erythroid transcription factor) binding protein 3 (GATA3) null embryo from early embryonic lethality_x000D_ Packaging_x000D_ 5, 10, 25, 50, 100 g in glass bottle_x000D_ Biochem/physiol Actions_x000D_ α1-adrenoceptor agonist._x000D_ Features and Benefits_x000D_ This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more._x000D_ This compound is featured on the α1-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here._x000D_ This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here._x000D_ Legal Information_x000D_ LOPAC is a registered trademark of Sigma-Aldrich Co. LLC