Description_x000D_ Biochem/physiol Actions_x000D_ RACK1 (receptor of activated protein kinase C1) is an intracellular adapter protein, which belongs to a class of intracellular receptor proteins that bind activated members of the protein kinase C family. RACK1 serves as a scaffold protein for a wide range of kinases and membrane-bound receptors. RACK1 is a member of the tryptophane-aspartate (WD) family known for its propeller-like structure. Literature strongly indicates that RACK1 plays an important role in intracellular signaling at several functional levels. RACK1, a substrate for several kinases, is involved in the regulation of Src function and cell growth._x000D_ Physical form_x000D_ Supplied in a 0.2 μm filtered solution of 0.02 M Tris buffer, pH 8.0, with 0.15 M NaCl, 5 mM DTT, 0.1% CHAPS, and 30% glycerol (w/v).