Description_x000D_ General description_x000D_ Resistin is a new member to of the family of adipocyte-secreted proteins. The biological functions of resistin, as well as its molecular target, are largely unknown. Whether it promotes or antagonizes insulin action is still unclear. Recombinant rat Resistin is an 11.9 kDa protein consisting of 94 amino acid residues and 16 additional amino acids residues-His Tag._x000D_ Resistin is an adipocytokine secreted by fat tissues and is localized to pancreatic α-cells in rat._x000D_ Application_x000D_ Resistin from rat has been used to study the effect of resistin on gonadotropins and local ovarian hormone-induced steroidogenesis._x000D_ Biochem/physiol Actions_x000D_ Resistin mediates energy homeostasis and inflammation process. Upregulation of resistin is observed in obesity. It is also known to increase blood glucose level and might promote insulin resistance. Thus, it might influence type 2 diabetes. Resistin might be linked to insulin resistance mediated myocardial infarction (MI). In rats, overexpression of resistin is observed in myocardial infarction and cardiac dysfunction._x000D_ Physical form_x000D_ Lyophilized from 20 mM Tris, pH 8.0._x000D_ Reconstitution_x000D_ Centrifuge the vial prior to opening. Avoid freeze-thaw cycles._x000D_ Reconstitute in water to a concentration of 0.1-1.0 mg/mL. This solution can then be diluted into other aqueous buffers.