Description_x000D_ Application_x000D_ S15535 may be used in histamine 5-HT1A-medaited cell signaling studies._x000D_ Packaging_x000D_ 25 mg in glass bottle_x000D_ Biochem/physiol Actions_x000D_ S15535, a benzodioxane, is a selective but partial agonist of histamine 5-HT1A receptor. It activates presynaptic 5-HT1A receptors and suppresses the release of hippocampal 5-HT. It acts as anxiolytic agent and modulates the cholinergic and cognitive function in rodents.3,4_x000D_ Potent, orally active, partial 5-HT1A receptor agonist_x000D_ Features and Benefits_x000D_ This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more._x000D_ Legal Information_x000D_ LOPAC is a registered trademark of Sigma-Aldrich Co. LLC