Description_x000D_ Application_x000D_ Sal003 was used to study the role of eIF2α in Subtilase cytotoxin-induced apoptosis in HeLa cells._x000D_ Packaging_x000D_ 5, 25 mg in glass bottle_x000D_ Biochem/physiol Actions_x000D_ Sal003 inhibits the late long-term potentiation (L-LTP) and long-term memory formation in mammalian hippocampal slices. The effect of Sal003 on L-LTP is mediated by the transcription factor, ATF4._x000D_ Sal003 is a potent and cell-permeable eIF-2a phosphatase inhibitor.