Description Application Samarium(II) iodide solution (SmI2) can be used as a reagent in the synthesis of: • Benzannulated pyrrolizidines and indolizidines by SmI2-induced cyclizations of indole derivatives. • Chiral 4-substituted 2-oxazolidinones and 5,5-disubstituted oxazolidinones through asymmetric Reformatsky type reaction. • γ-Aminoalkyl substituted γ-butyrolactones via ketyl-alkene coupling reaction. SmI2 can also be used in: • Reduction of conjugated double and triple bonds into alkenes using SmI2/H2O/amine mixtures. • Conversion of β-hydroxyketones into 1,3-diols by SmI2/H2O/Et3N. • Selective reduction of 6-membered lactones to the corresponding diols/triols using SmI2-H2O reagent system. Packaging 1 L in Sure/Seal™ 25, 4×25, 100 mL in Sure/Seal™ The 25 mL Sure/Seal™ bottle is recommended as a single-use bottle. Repeated punctures will likely result in decreased performance of product. Legal Information Sure/Seal is a trademark of Sigma-Aldrich Co. LLC