Description_x000D_ Application_x000D_ SFLLR-NH2 trifluoroacetate salt may be used in cell signaling and immunology studies._x000D_ Packaging_x000D_ 1 mg in glass bottle_x000D_ Biochem/physiol Actions_x000D_ SFLLR-NH2 is a PAR-1 (Protease-Activated Receptor) selective activating peptide, also known as Thrombin Receptor Activating Peptide 5 (TRAP-5). Protease-activated receptors (PARs) are present on various organs including, platelets, mast cell, gallblader, oesophagus etc, and regulate various physiological processes including human platelet aggregation, vascular contraction/relaxation, and an increase in endothelial permeability. Recent papers indicated that PAR′s are also involved in sensory processing and proliferation of astrocytes.