Description General description A cell-permeable pyrrolopyridine compound that selectively inhibits TGF-β1-dependent Smad3 phosphorylation and Smad3-mediated cellular signaling with no effect on Smad2, p38 MAPK, ERK, or PI 3-K signaling. Packaging 1 mg in Plastic ampoule Biochem/physiol Actions Cell permeable: yes Primary Target TGF-β1-dependent Smad3 phosphorylation and Smad3-mediated cellular signaling Product does not compete with ATP. Reversible: no Packaging Packaged under inert gas Warning Toxicity: Irritant (B) Reconstitution Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Other Notes Jinnin, M., et al. 2006. Mol. Pharmacol.69, 597.