Description_x000D_ Application_x000D_ SR 57227A may be used in 5-HT3-mediated cell signaling studies._x000D_ Packaging_x000D_ 5 mg in glass bottle_x000D_ Biochem/physiol Actions_x000D_ SR 57227A is a highly selective of central and peripheral 5-HT3 receptors and an inhibitor of NMDA receptor-mediated responses in rat cortical pyramidal cells. It exhibits anti-depressant like effects in rats and decreased isolation-induced aggressive behavior._x000D_ Potent and selective 5-HT3 serotonin receptor agonist.