Description_x000D_ Application_x000D_ Stevioside hydrate has been used as a standard in high performance liquid chromatography (HPLC) for quantification of steviol glycosides._x000D_ Stevioside-induced ROS-mediated apoptosis was studied in human breast cancer cells._x000D_ Packaging_x000D_ 10, 50 mg in glass bottle_x000D_ Biochem/physiol Actions_x000D_ Stevioside hydrate is a diterpene glycoside present in Stevia sp._x000D_ Stevioside is a noncaloric natural sweetener, 300 times more potent than sucrose. It inhibits transepithelial transport of p-aminohippurate (PAH) by interfering with the organic anion transport system. At 0.5-1 mM, it showed no interaction with any organic anion transporters (OAT)._x000D_ Stevioside reportedly has genotoxic effects in cultured mammalian cells._x000D_ Features and Benefits_x000D_ This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more._x000D_ Preparation Note_x000D_ Stevioside solutions should be prepared in DMSO. Highly pure stevioside has very poor water solubility._x000D_ Legal Information_x000D_ LOPAC is a registered trademark of Sigma-Aldrich Co. LLC