Description_x000D_ General description_x000D_ Chemical structure: sulfonamide_x000D_ Application_x000D_ Sulfathiazole is a short-acting sulfa drug. It was a common oral and topical antibiotic until less toxic alternatives were discovered. It is no longer used in humans. Sulfathiazole is added to the diet of laboratory animals to inhibit folate formation by gut bacteria. This ensures that the animal’s only source of available folate is from their diet._x000D_ Packaging_x000D_ 100 g in poly bottle_x000D_ Biochem/physiol Actions_x000D_ Sulfathiazole is a sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase. Sulfathiazole is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid. It is active against Gram positive bacteria, Gram negative bacteria and Chlamydia. Mode of resistance is via the alteration of dihydropteroate synthase or alternative pathway for folic acid synthesis._x000D_ Other Notes_x000D_ Keep container tightly closed in a dry and well-ventilated place.