Description_x000D_ Packaging_x000D_ 5, 25 mg in glass bottle_x000D_ Biochem/physiol Actions_x000D_ TAE-1 is an inhibitor of amyloid-β fibril formation and aggregation. TAE-1 is a sym-triazine with dual activity against Alzheimer′s disease. TAE-1 inhibits cholinesterases AChE and BuChE with IC50 values of 0.3 and 3.9 μM. Studies using TAE-1 on differentiated human SH-SY5Y neuronal cells have suggested that it can stimulate synapse formation and promote the differentiation of human neurons, increasing neurite extension._x000D_ Features and Benefits_x000D_ This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.