Description_x000D_ General description_x000D_ Allylamine derivative._x000D_ Application_x000D_ Terbinafine hydrochloride is a synthetic allylamine antifungal. It is used to treat dermatophyte infections of the toenail/fingernail, ringworm and jock itch. It is used in adsorption, partition and stability studies._x000D_ Packaging_x000D_ 100, 250 mg in poly bottle_x000D_ Biochem/physiol Actions_x000D_ Terbinafine inhibits squalene monooxygenase thereby blocking the biosynthesis of ergosterol, which is an essential component of fungal cell membranes. The inhibition of squalene monooxygenase also results in the accumulation of squalene. Terbinafine hydrochloride is highly lipophilic and tends to accumulate in skin, nails, and fatty tissues. It is antifungal and antimycotic. It is fungicidal against dermatopytes and some yeasts and is fungistatic against Candida albicans._x000D_ Mode of Action: Inhibits squalene epoxidase, preventing biosynthesis of ergosterol._x000D_ Antimicrobial spectrum: Antifungal and antimycotic. Fungicidal against dermatopytes and some yeasts; fungistatic against Candida albicans._x000D_ Other Notes_x000D_ Keep container tightly closed in a dry and well-ventilated place.Keep in a dry place.