Description_x000D_ General description_x000D_ Thyrotropin/thyroid-stimulating hormone (TSH) belongs to the glycoprotein hormone family. This glycoprotein is produced by thyrotroph cells of the anterior pituitary gland. It circulates in free form and possess a short plasma half-life._x000D_ Application_x000D_ Thyrotropic hormone from bovine pituitary can be used for TSH stimulation test for assessing the thyroid gland function after NTI induction. The product was injected in 4-week-old male C57BL/6J and CBA/N mice for studying the thyrotropin involvement in photoperiodic signal transduction._x000D_ Thyrotropic hormone from bovine pituitary has been used to induce cAMP production in orbital fibroblasts. It has also been used as a component in Dulbecco modified eagle medium (DME) H-21:F-12 media._x000D_ Packaging_x000D_ 1 vial in serum bottle_x000D_ 10 vials in serum bottle_x000D_ Biochem/physiol Actions_x000D_ Thyrotropin/thyroid-stimulating hormone (TSH) helps to regulate thyroid function. In children, TSH plays a vital role in normal cognition and neurodevelopment. Circulating TSH is capable of binding to cell surface receptors in the thyroid gland. This hormone induces thyroid to produce thyroglobulin and the thyroid hormones. TSH can also promote the uptake of iodine (131I) in individuals with thyroid cancer._x000D_ Two-chain glycoprotein hormone. The α-chain is not active, biological specificity attributed rather to the β-chain. Activates adenylate cyclase in the thyroid gland, stimulating iodine uptake, thyroxine synthesis and release. Goitrogenic._x000D_ Quality_x000D_ Contains phosphate buffer salts