Description_x000D_ General description_x000D_ Toremifene is a triphenylethylene derivative. It exhibits antitumor and antiestrogen effects. Toremifene has estrogen-agonist effects on blood lipids and endometrium._x000D_ Application_x000D_ Toremifene citrate salt has been used:_x000D_ • in cell-based ELISA_x000D_ • as a positive control to detect its antiviral activity against Ebola virus (EBOV)_x000D_ • to treat MCF7 and T47D breast cancer cell lines_x000D_ Packaging_x000D_ 5, 25 mg in glass bottle_x000D_ Biochem/physiol Actions_x000D_ Toremifene citrate is an oral selective estrogen receptor modulator (SERM). It is used in advanced (metastatic) breast cancer and being evaluated for prevention of prostate cancer. Toremifene citrate is known to increase bone mineral density in prostate cancer patients undergoing androgen deprivation therapy†._x000D_ Features and Benefits_x000D_ This compound is featured on the Nuclear Receptors (Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here._x000D_ Preparation Note_x000D_ Toremifene citrate salt is soluble in DMSO at a concentration that is greater than 10 mg/ml.