Description_x000D_ Application_x000D_ TRAM-34 has been used to study its effect on the prevention of vascular restenosis after balloon angioplasty._x000D_ Packaging_x000D_ 5, 25 mg in glass bottle_x000D_ Biochem/physiol Actions_x000D_ TRAM-34 exhibits 100-fold selectivity (Kd = 20 nM) for IKCa1 channels over other K+ channels (Charybdotoxin, Kd = 5 nM, Clotrimazole, Kd = 70 nM; Nitrendipine Kd = 900 nM). Furthermore, TRAM-34 is known to suppress the activation of human T lymphocytes,._x000D_ TRAM-34 is a potent inhibitor of the intermediate-conductance Ca2+-activated K+ channel._x000D_ Features and Benefits_x000D_ This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here._x000D_ Preparation Note_x000D_ TRAM-34 is soluble in DMSO at 2 mg/ml. However, it is insoluble in water.