Description General description Tributylphosphine (TBP) is a potential nucleophile. It acts as a weak base in organic solvents. It is an important catalyst for the acylation reactions. It is an efficient promoting reagent for the ring-opening reaction of various epoxides and aziridines. TBP in conjugation with 1,1′-(azodicarbonyl)dipiperidine (ADDP) constitutes Mitsunobu reagent. This reactive phosphine allows the formation of a strained lactone. Application Tributylphosphine was used in the preparation of silver nanoparticles (AgNPs) functionalized with an organometallic bifunctional thiol containing Pt(II) centers. It may be used in the following processes: • As reducing agent for alkyl disulfides and aromatic disulfides. • As catalyst for the synthesis of 2-substituted 1,3-benzoselenazoles. • As promoter for the ring opening of epoxides and aziridines with nucleophiles. • As a reagent in the preparation of 6-substituted penicillanate esters by reduction of 6-bromo-6-substituted penicillanate esters in high diastereoselectivity. • As a catalyst in the acylation reaction of alcohols. • As a catalyst to prepare rotaxanes by the acylation of corresponding pseudorotaxanes using 3,5-dimethylbenzoic anhydride. • As a catalyst to prepare vinyl thioethers by the Michael addition of ethanethiol to various alkynyl ketones. • As a promoter in the conjugate addition of non-nucleophilic N-containing compounds with Michael acceptors. Packaging 25, 100, 500 mL in Sure/Seal™