Description_x000D_ Application_x000D_ The interaction of Trifluperidol hydrochloride with NMDA receptors was studied in rat brain buffy coat membranes._x000D_ Packaging_x000D_ 25, 100 mg in glass bottle_x000D_ Biochem/physiol Actions_x000D_ Trifluperidol is a dopamine receptor antagonist with antipsychotic effects used in the treatment of schizophrenia. This neuroleptic penetrates the brain and also affects the glial cells leading to increased release of proinflammatory cytokines. It also alters the metabolism of carbohydrates and amino acids in the brain cortex._x000D_ Features and Benefits_x000D_ This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more._x000D_ Legal Information_x000D_ LOPAC is a registered trademark of Sigma-Aldrich Co. LLC