Description_x000D_ Application_x000D_ Trioxsalen has been used for mutagenesis of N2 worms4,5._x000D_ Trioxsalen has been used:_x000D_ • to induce small deletion mutations in worms_x000D_ • in combination with ultraviolet A (UVA)_x000D_ • to induce interstrand crosslinks (ICLs) in DNA_x000D_ • for the preparation and photoactivation of trimethyl psoralen_x000D_ Packaging_x000D_ 1 g in glass bottle_x000D_ 100, 500 mg in glass bottle_x000D_ Biochem/physiol Actions_x000D_ Photochemical crosslinker of DNA that has been used as a probe for nucleic acid structure and function. Trioxsalen has also been used to crosslink DNA onto mica surfaces._x000D_ Trioxsalen (TRX) is a 4,5′,8-trimethylated psoralen analog, which belongs to the family of furocoumarins. It is mostly used to treat psoriasis._x000D_ Features and Benefits_x000D_ This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm._x000D_ This compound was developed by Valeant. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here._x000D_ Preparation Note_x000D_ Trioxsalen is soluble in chloroform at 50 mg/ml and yields a clear, colorless to faint yellow solution.