Description_x000D_ Application_x000D_ Triparanol has been used to inhibit cholesterol biosynthesis in lipid rafts1. Triparanol has also been used as a 3β-hydroxysterol-δ24-reductase inhibitor to study its effect on delayed-rectifier potassium current (Iks) channels2._x000D_ Packaging_x000D_ 5, 25 mg in glass bottle_x000D_ Biochem/physiol Actions_x000D_ Triparanol is known to repress Hedgehog signaling in cancer cells and can also inhibit tumor growth3._x000D_ Desmosterol Delta24 (D24) reductase inhibitor._x000D_ Preparation Note_x000D_ Triparanol is soluble in DMSO at 20 mg/ml and is also soluble in alcohol. It is slightly soluble in olive oil and is insoluble in water._x000D_ Other Notes_x000D_ Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. T5200.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.