Description General description Indole alkaloid that binds to tubulin, inhibiting formation of microtubules. Depolymerizes microtubules. Induces increase in micronuclei and delays cell cycle progression. Anti-neoplastic agent. Induces apoptosis in human lymphoma cells by disrupting microtubules. Please note that the molecular weight for this compound is batch-specific due to variable water content. Indole alkaloid that binds to tubulin, inhibiting the formulation of microtubules. Depolymerizes microtubules. Induces an increase in the micronucleus and delays cell cycle progression. Antineoplastic agent. Induces apoptosis in human lymphoma cells by distributing microtubules. Packaging 10 mg in Plastic ampoule Biochem/physiol Actions Cell permeable: no Product does not compete with ATP. Reversible: no Warning Toxicity: Carcinogenic / Teratogenic (D) Other Notes Chan, M.W., et al. 1998. Cancer Biochem. Biophys. 16, 347. Hanauske, A.R., et al. 1994. Eur. J. Cancer30A, 1688. Takano, Y., et al. 1993. Pathol. Res. Pract. 189, 187.