Description General description We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product has been used as a catalyst. Find details here. XPhos [2-Dicyclohexylphosphino-2′,4′,6′-triisopropylbiphenyl] is an air-stable electron-rich biaryl monophosphine ligand2 developed by the Buchwald group to enhance the reactivity of palladium catalysis during cross-coupling reactions. Application Ligand used in a Pd-catalyzed Suzuki coupling leading to C-15 analogs of vindoline. Direct annulation of 2-haloanilines to indoles and tryptophans catalyzed by Pd. Synthesis of regioregular polythiophenes. Preferred ligand for greener Sonogashira coupling in TPGS-750-M. Preferred ligand for greener Sonogashira coupling in TPGS-750-M. On the Way Towards Greener Transition-Metal-Catalyzed Processes as Quantified by E Factors XPhos may be used as a ligand in the following reactions: • Preparation of functionalized benzylic sulfones via palladium-catalyzed Negishi cross-coupling between alkyl sulfones and aryl halides. • Along with pre-milled palladium(II) acetate as a pre-catalyst for the Stille cross-coupling of aryl chlorides with tributylarylstannanes to form the corresponding biaryl compounds. • Along with platinum chloride to catalyze the hydrosilylation of terminal arylalkynes with silanes to form functionalized β-(E)-vinylsilanes. Ligand for increased scope of Pd-catalyzed amination and amidation via arene sulfonates, aryl halides. Packaging 1, 5, 25, 100, 500 g in glass bottle Legal Information Usage subject to US Patent 7,223,879 Usage subject to US Patents 6307087 and 6395916.